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Polycythemia vera in a dog presenting with uveitis.
Heather E Gray1, Claire M Weigand, Nancy B Cottrill
1Department of Internal Medicine, Rowley Memorial Animal Hospital, 171 Union Street, Springfield, Massachusetts 01105, USA.
Journal of the American Animal Hospital Association
|July 23, 2003
Summary
Polycythemia vera, a condition of increased red blood cells, can manifest with eye inflammation and vomiting in dogs. Treatment involving blood removal and medication led to full recovery.
Area of Science:
- Veterinary Medicine
- Ophthalmology
- Hematology
Background:
- Polycythemia vera is a rare myeloproliferative neoplasm characterized by excessive red blood cell production.
- Ocular manifestations in canine polycythemia vera are not well-documented, presenting diagnostic challenges.
Observation:
- A 2-year-old dog presented with ocular inflammation (uveitis, chorioretinitis), vomiting, and increased thirst/urination.
- Diagnostic workup revealed an elevated red blood cell mass, with a low-normal erythropoietin level.
Findings:
- The clinical signs and laboratory findings were consistent with a diagnosis of polycythemia vera.
- Ophthalmic examination revealed bilateral anterior uveitis and active chorioretinitis.
Implications:
- This case highlights the importance of considering polycythemia vera in dogs with concurrent systemic and ocular abnormalities.
- Successful management with phlebotomy and hydroxyurea suggests a viable therapeutic strategy for this condition.