Related Experiment Video

Updated: Sep 14, 2026

Nucleoside Triphosphates - From Synthesis to Biochemical Characterization
15:22

Nucleoside Triphosphates - From Synthesis to Biochemical Characterization

Published on: April 3, 2014

Oligonucleotides with strongly fluorescent groups pi-conjugated to a nucleobase: syntheses, melting temperatures, and

Guan-Sheng Jiao1, Kevin Burgess

  • 1Department of Chemistry, PO Box 30012, Texas A & M University, College Station, TX 77842-3012, USA.

Bioorganic & Medicinal Chemistry Letters
|July 23, 2003
PubMed

Abstract:

Phosphoramidite 1 was prepared, incorporated into oligonucleotides, and these were studied via thermal denaturation and circular dichroism.

More Related Videos

Synthesis of Wavelength-shifting DNA Hybridization Probes by Using Photostable Cyanine Dyes
07:44

Synthesis of Wavelength-shifting DNA Hybridization Probes by Using Photostable Cyanine Dyes

Published on: July 6, 2016

Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids
09:04

Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids

Published on: September 21, 2017

Related Experiment Videos

Last Updated: Sep 14, 2026

Nucleoside Triphosphates - From Synthesis to Biochemical Characterization
15:22

Nucleoside Triphosphates - From Synthesis to Biochemical Characterization

Published on: April 3, 2014

Synthesis of Wavelength-shifting DNA Hybridization Probes by Using Photostable Cyanine Dyes
07:44

Synthesis of Wavelength-shifting DNA Hybridization Probes by Using Photostable Cyanine Dyes

Published on: July 6, 2016

Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids
09:04

Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids

Published on: September 21, 2017

Related Concept Videos

Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...

Articles linked to this work by shared authors, journal, and citation graph.

Correction: Forces behind N- and C-capping of peptidic helices.

Chemical communications (Cambridge, England)·2026

Novel Neurotrophin-3 peptidomimetic synthetic neurotrophin promotes neurological recovery after spinal cord injury.

Experimental neurology·2026

PROTACs for Collateral Degradation: Is It Time to Back Up the Bus?

ACS medicinal chemistry letters·2026

Forces behind N- and C-capping of peptidic helices.

Chemical communications (Cambridge, England)·2026

Cancer immunotherapeutic targeting tropomyosin receptor kinase C (TrkC) through its conjugate and cyclophosphamide.

Immunopharmacology and immunotoxicology·2025

Small-Molecule Trk Agonists: Where Do We Go from Here?

Journal of medicinal chemistry·2025

Photocaging of a GPR52 agonist enables light-dependent receptor activation in cells.

Bioorganic & medicinal chemistry letters·2026

The antiproliferative and pro-apoptotic effects of 3-deoxy-3α-fluoro-chenodeoxycholic acid and 12β-methyl-3,7-dioxo-17-epi-25-homo-18-nor-5β-cholan-25-oic acid on human breast cancer cell lines.

Bioorganic & medicinal chemistry letters·2026

Discovery of potent, selective, and orally bioavailable monocyclic pyridine-based PKMYT1 inhibitors that synergize with CHK1 inhibition in replication-stressed cancer cells.

Bioorganic & medicinal chemistry letters·2026

Quinolin(on)es and pyridin(on)es as promising scaffolds against mycobacterial infections.

Bioorganic & medicinal chemistry letters·2026

Amyloid-β aggregation inhibitory activity and neuroprotective effects of metabolites of Trichoderma pluripenicillatum.

Bioorganic & medicinal chemistry letters·2026

Electrophilic aromatic halogenation of perylenequinones: a strategy to improve photodynamic properties.

Bioorganic & medicinal chemistry letters·2026

Raman Evaluation of the Crystallinity Degree of Star-Shaped Lactide Oligomers: An Influence of the Number, Length and Enantiomeric Composition of the Arms.

Polymers·2026

Microemulsions of Essential Oils: Characterization and Phase Behavior.

International journal of molecular sciences·2026

Concentration-Dependent Modulation of Fibrillated Egg White Protein by γ-Cyclodextrin: Structural, Emulsifying, and Rheological Properties of Oil-in-Water Emulsions.

Foods (Basel, Switzerland)·2026

Atomic Force Microscopy-Based Nanomechanical Profiling Reveals Oxidative Stress-Associated Structural Alterations and Curcumin-Associated Protection in Chicken Erythrocytes.

Current issues in molecular biology·2026

Permeation behaviour of cosmetic actives into the human stratum corneum.

International journal of pharmaceutics·2026

Metalation-controlled charge-selective capture of dye pollutants and iodine by free-base and Zn-porphyrin-based ionic organic polymer adsorbents.

Talanta·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us