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Optical-fiber-based Mueller optical coherence tomography.

Shuliang Jiao1, Wurong Yu, George Stoica

  • 1Optical Imaging Laboratory, Department of Biomedical Engineering, Texas A&M University, 3120 TAMU, College Station, Texas 77843-3120, USA.

Optics Letters
|July 30, 2003
PubMed
Summary
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This study introduces a novel fiber-based polarization-sensitive Optical Coherence Tomography (OCT) system. It dynamically calibrates to correct for polarization distortion, enabling accurate imaging of biological tissues.

Area of Science:

  • Biomedical Optics
  • Optical Engineering
  • Medical Imaging

Background:

  • Polarization-sensitive Optical Coherence Tomography (PS-OCT) is valuable for characterizing scattering media like biological tissues.
  • The application of fiber-based PS-OCT has been hindered by polarization distortion introduced by optical fibers.
  • Accurate measurement of polarization properties requires overcoming these fiber-induced distortions.

Purpose of the Study:

  • To develop and validate a fiber-based multichannel polarization-sensitive Mueller Optical Coherence Tomography (OCT) system.
  • To implement dynamic calibration for eliminating polarization distortion in the sample arm's optical fiber.
  • To enable accurate acquisition of Jones or Mueller matrices for scattering media.

Main Methods:

Related Experiment Videos

  • An optical-fiber-based multichannel polarization-sensitive Mueller OCT system was constructed.
  • Dynamic calibration was performed by acquiring the round-trip Jones matrix of the sampling fiber for each A-scan.
  • A rigorous algorithm was developed and applied to retrieve calibrated polarization properties.

    • Main Results:

    • The system successfully acquired Jones or Mueller matrices of scattering media.
    • Dynamic calibration effectively eliminated polarization distortion from the single-mode optical fiber.
    • The developed algorithm accurately retrieved sample polarization properties, validated by experimental data.

    Conclusions:

    • The developed fiber-based PS-OCT system with dynamic calibration overcomes a key technical challenge.
    • This advancement facilitates the application of fiber-based OCT for in-situ polarization-sensitive imaging.
    • The system was successfully demonstrated by imaging rat skin.