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Related Experiment Videos

Can IQCODE detect poststroke dementia?

Wai Kwong Tang1, Sandra S M Chan, Helen F K Chiu

  • 1Department of Psychiatry, Chinese University of Hong Kong, Hong Kong, SAR, China. tangwk@cuhk.edu.hk

International Journal of Geriatric Psychiatry
|August 2, 2003
PubMed
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The Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) showed low utility in screening post-stroke dementia (PSDE) in Chinese elderly. Its positive predictive value was only 33%, suggesting it is not a reliable sole screening tool.

Area of Science:

  • Neurology
  • Geriatrics
  • Psychiatry

Background:

  • Limited data exists on the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) for post-stroke dementia (PSDE) screening.
  • Investigating the IQCODE's utility in a Chinese elderly population is crucial.

Purpose of the Study:

  • To evaluate the performance of the IQCODE in screening post-stroke dementia (PSDE) among Chinese elderly patients.
  • To determine the diagnostic accuracy of IQCODE compared to a gold standard psychiatric diagnosis.

Main Methods:

  • The IQCODE was administered to relatives of 189 acute stroke patients at 3 months post-stroke.
  • A psychiatrist, blinded to IQCODE scores, diagnosed dementia using DSM-IV criteria as the benchmark.
  • Statistical analysis included sensitivity, specificity, predictive values, and ROC curve analysis.

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Main Results:

  • The optimal IQCODE cut-off score was identified as 3.40.
  • IQCODE demonstrated 88% sensitivity and 75% specificity for PSDE screening.
  • The positive predictive value was 33%, and the negative predictive value was 98%, with an AUC of 0.88.

Conclusions:

  • The IQCODE, when used alone, is not sufficiently effective for screening post-stroke dementia in the Chinese elderly population.
  • The low positive predictive value indicates a high rate of false positives, limiting its clinical utility as a standalone tool.