[Morphometric characteristics of the kidney nephrogenic zone in newborn rats]

The aim of this work was to give a quantitative characteristic of nephronogenesis and to select the morphometric criteria, which adequately reflect the dynamics of morphogenetic processes. As the study object, the nephrogenic zone of a newborn rat kidney was used, that was examined in sections stained using histological and histochemical methods. The development of nephron structures and of the stroma was followed, and it was established that grading the degree of differentiation of the structures, comparison the nephrogenic zone, reflects the system of current concepts on the inter-inductive influences, which are realized between the distal portions of collecting ducts and nephrogenic cells, epitheliocytes of developing tubules and stromal cells. The morphometric parameters obtained could be used for interpretation of the data on the velocity of nephron formation and tubulogenesis, as well as on the intensity and quality of vascular glomeruli formation.