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Published on: November 30, 2016
Prevalence of microscopic colitis in patients with symptoms suggesting irritable bowel syndrome
C Tunçer1, M Cindoruk, A Dursun
1Gazi University Faculty of Medicine, Department of Gastroenterology, Ankara.
Goals/Background:
Irritable bowel syndrome is a common disorder affecting 20% of the general population. It shows certain characteristics with organic bowel diseases. Definition of lymphocytic and collagenous colitis has created a new approach towards chronic idiopathic diarrheas. We searched for the frequency of lymphocytic and collagenous colitis in patients with irritable bowel syndrome.
Study:
The study group consisted of 30 irritable bowel patients and 20 controls. Multiple biopsies from cecum; ascendant, transverse and descendent colon; sigmoid and rectum were taken sequentially in all patients.
Results:
We diagnosed 7 out of 30 irritable bowel patients as having lymphocytic colitis (23.3%) but none as having collagenous colitis. In the control group 1 out of 20 patients had lymphocytic colitis (5%) and none had collagenous colitis. Irritable bowel patients had higher rate of lymphocytic colitis association (p < 0.05).
Conclusions:
Functional disorders of the bowel should be searched for possible lymphocytic colitis, especially in cases refractory to classical therapies.
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