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[Indifferentiated rheumatism and/or epileptic flatulence].

R Veiga Cabello1, J R Toral Revuelta, E Sánchez Sánchez

  • 1Servicio de Reumatología, Medicina Interna. Hospital del Aire. Madrid, Spain. med028714@nacom.es

Anales De Medicina Interna (Madrid, Spain : 1984)
|August 2, 2003
PubMed
Summary

A case study highlights a woman with autoimmune disorders and tumors, who experienced unexplained flatulence. This symptom may represent a rare form of abdominal epilepsy linked to a brain tumor.

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Area of Science:

  • Rheumatology
  • Neurology
  • Oncology

Background:

  • A 50-year-old woman presented with symptoms suggestive of dry syndrome and immune dysregulation.
  • She also developed benign tumors and presented with analytical autoimmunity, including positive anti-topoisomerase I (formerly Scl70) antibodies.

Observation:

  • The patient experienced significant meteorism (abdominal bloating and gas).
  • The clinical presentation included autoimmune markers and tumor development.

Findings:

  • Autoimmune markers, specifically anti-topoisomerase I antibodies, confirmed analytical autoimmunity.
  • A potential link between meteorism and a right-sided convexity meningioma was explored, suggesting a variant of abdominal epilepsy presenting as ictal flatulence.

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Implications:

  • This case underscores the complex interplay between autoimmune diseases, tumor development, and neurological manifestations.
  • It highlights the importance of considering rare neurological presentations, such as abdominal epilepsy, in patients with autoimmune disorders and unexplained symptoms.
  • Further research into the neuro-immune-endocrine axis in such conditions is warranted.