A conserved domain in axonal targeting of Kv1 (Shaker) voltage-gated potassium channels

Chen Gu1, Yuh Nung Jan, Lily Yeh Jan

  • 1Howard Hughes Medical Institute, Departments of Physiology and Biochemistry, University of California, San Francisco, CA 94143-0725, USA.

Science (New York, N.Y.)
|August 2, 2003
PubMed

Related Concept Videos

Electric Field Lines01:25

Electric Field Lines

The three-dimensional representation of the electric field of a positive point charge requires tracing the electric field vectors, whose lengths decrease as the square of their distance from the charge and which point away from the charge at each point. This vector field is no doubt challenging to visualize. The visualization of electric fields becomes quickly intractable as the number of charges increases.
The solution to this problem is to use electric field lines, which are not vectors but...
Electric Field of a Charged Disk01:23

Electric Field of a Charged Disk

The simplest case of a surface charge distribution is the uniformly charged disk. Calculating its electric field also helps us calculate the electric field of a large plane of charge.
The system's symmetry is in the cylindrical directions across the plane of the charge. As a result, the electric fields created by various surface charge elements nullify each other in the direction parallel to the surface. Thereby, the resulting electric field is perpendicular to the plane. Since the disk is...
Kirchhoff's Voltage Law01:04

Kirchhoff's Voltage Law

Kirchhoff's Voltage Law (KVL) is another fundamental principle in electrical engineering, introduced by physicist Gustav Robert Kirchhoff. This law is rooted in the principle of energy conservation, which states that energy can neither be created nor destroyed, only transferred or converted from one form to another.
KVL states that the algebraic sum of all voltages around a closed path or loop within a circuit is zero. This means that the total voltage supplied in a loop is equal to the total...
The Delta-to-Delta Circuit01:17

The Delta-to-Delta Circuit

In a delta-delta configuration, the source and the load are connected in a delta manner, forming a closed loop that divides the network into three distinct phases. This configuration makes the phase voltages identical to line voltages. Assuming the sources are in positive sequence, the phase voltages can be expressed directly without having a neutral wire.
Radial System Protection01:23

Radial System Protection

Radial systems employ time-delay overcurrent relays to reduce load interruptions. When a fault occurs, the nearest breaker opens first, while upstream breakers remain closed due to longer delay settings. This approach ensures minimal disruption to the rest of the system.
In a radial system with a fault downstream of the third breaker, ideally, only the third breaker will open, isolating the fault and interrupting the load connected beyond it. The second breaker has a longer delay setting,...
Zones of Protection01:16

Zones of Protection

In power systems, the entire setup is divided into protective zones to isolate faults and protect the rest of the network. These zones include generators, transformers, buses, transmission lines, distribution lines, and motors. Each zone can be visualized as a separate room in a house, with each room protected by its own circuit breaker.
Protective zones are defined by closed dashed lines, containing one or more components. A key characteristic of these zones is the strategic placement of...