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Investigational therapies for psoriasis
Jennifer Clay Cather1, John Christian Cather, William Abramovits
1Texas Dermatology Associates, 5310 Harvest Hill, Dallas, TX 75230, USA. research@texasderm.com
Journal of the American Academy of Dermatology
|August 2, 2003
Summary
New targeted therapies for psoriasis are emerging. This review covers promising investigational treatments and their mechanisms of action, building on current biologic therapies.
Area of Science:
- Dermatology
- Immunology
- Pharmacology
Background:
- Psoriasis pathogenesis understanding is advancing.
- Biologic therapies like alefacept, etanercept, efaluzimab, and infliximab are established treatments.
- Numerous investigational therapies are in clinical trials.
Purpose of the Study:
- To review promising investigational therapies for psoriasis.
- To describe the mechanisms of action for these novel treatments.
Main Methods:
- Literature review of clinical trials and scientific publications.
- Analysis of emerging targeted therapies for psoriasis.
Main Results:
- Identification of several promising investigational psoriasis therapies.
- Detailed description of their proposed mechanisms of action.
Conclusions:
- The pipeline for novel psoriasis treatments is robust.
- Future approvals are anticipated, offering more therapeutic options.