Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Aneurysmal model induced by elastase].

K Yin1, Y L Ding, Z X Wu

  • 1Department of Interventional Neuroradiology, Beijing Neurosurgical Institute, CAMS, Beijing 100050, China.

Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
|August 9, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Analysis of posterior uterus approach combined with vascular occlusion in placenta percreta].

Zhonghua fu chan ke za zhi·2026
Same author

[Role of the JAK2/STAT3 pathway in aluminium-induced synaptic function impairment].

Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases·2026
Same author

[Study on the correlation between dust mite component values and allergic rhinitis with or without asthma].

Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]·2026
Same author

[Construction and validation of a prognostic prediction model for children-onset initial steroid-resistant nephrotic syndrome].

Zhonghua er ke za zhi = Chinese journal of pediatrics·2026
Same author

[Health risk assessment of <i>Pseudomonas aeruginosa</i> in source water of the Yangtze River Basin in China].

Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]·2026
Same author

[Define benchmarks for low-risk sleeve gastrectomy: based on the greater China metabolic and bariatric surgery database].

Zhonghua wai ke za zhi [Chinese journal of surgery]·2026
Same journal

Splenic Angiosarcoma Misdiagnosed as PrimaryMyelofibrosis: Report of Two Cases and a Literature Review.

Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae·2026
Same journal

Anesthetic Management for Epicardial Pacemaker Implantation in An Adult Patient With Uncorrected Functional Single Ventricle:A Case Report.

Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae·2026
Same journal

Magnetic Resonance Imaging Combined With Ultrasonography for Early Diagnosis of Complete Hydatidiform Mole With Coexisting Fetus: Report of One Case.

Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae·2026
Same journal

Prospects for China's Pharmaceutical Industry Development During the 15th Five-Year Plan Period.

Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae·2026
Same journal

[Comparison of Imaging Efficacy and Patient Tolerability Between a Novel Cellulose-Based anda Conventional Starch-Based Oral Contrast Agent: A Prospective Randomized Controlled Trial].

Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae·2026
Same journal

[Application Value of Super-Resolution Ultrasound Imaging in the Diagnosisof American College of Radiology Thyroid Imaging Reporting and Data System Category 4 and 5 Thyroid Nodules].

Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae·2026
See all related articles

Researchers created a new aneurysm model by corroding arterial walls with elastase. This method effectively mimics clinical intracranial aneurysms, offering a promising alternative for research.

Area of Science:

  • Vascular Biology
  • Pathology
  • Surgical Innovation

Context:

  • Intracranial aneurysms pose significant clinical challenges.
  • Existing aneurysm models have limitations in accurately replicating pathological features.
  • Elastase-induced arterial wall degradation offers a novel approach to aneurysm induction.

Purpose:

  • To develop a novel experimental model for intracranial aneurysms.
  • To mimic the patho-morphological characteristics of clinical intracranial aneurysms.
  • To evaluate the efficacy of elastase corrosion for aneurysm creation.

Summary:

  • Elastase-corroded arterial segments were transplanted onto carotid arteries.
  • Aneurysms formed were persistent or slightly enlarged within one month.

Related Experiment Videos

  • Pathological examination revealed walls lacking elastic layers and composed of thin connective tissue, with a tendency to rupture.

    • Impact:

    • This elastase-induced aneurysm model demonstrates good clinical mimicry.
    • The model is simple to construct, offering a viable alternative to venous pouch models.
    • Facilitates further research into aneurysm formation, rupture, and treatment strategies.