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Two new bromotyrosine-derived metabolites from the sponge Psammaplysilla purpurea
Thirumani Venkateshwar Goud1, Masuna Srinivasulu, Vanimireddy Lakshmi Niranjan Reddy
1Natural Products Laboratory, Organic Division-I, Indian Institute of Chemical Technology.
Chemical & Pharmaceutical Bulletin
|August 13, 2003
Abstract:
Two new bromotyrosine-derived metabolites (1, 2) have been isolated along with the known compounds 3,5-dibromo-4-methoxyphenylacetonitrile, 3-bromo-4-methoxyphenylacetonitrile, 3-bromo-4-hydroxyphenylacetonitrile, 1-hydroxyuracil, 1-methoxyhemibastadin 2, purpuramine H and a steroid 5alpha,8alpha-epidioxycholest-6-en-3beta-ol from the sponge Psammaplysilla purpurea. Compounds 1 and 2 were characterized by interpretation of their spectral data. The antibacterial activity of these compounds is summarized.