Risperidone-responsive segmental dystonia and pallidal deep brain stimulation
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Updated: Sep 20, 2026

Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation
Published on: July 16, 2014
J C Wöhrle1, R Weigel, E Grips
1Departments of Neurology,Universitätsklinikum, Mannheim, Germany. woehrle@neuro.ma.uni-heidelberg.de
Abstract:
A 67-year-old man with risperidone-responsive segmental dystonia underwent bilateral deep brain stimulation (DBS) of the globus pallidus internus. Prospectively, the authors assessed the Burke-Fahn-Marsden Dystonia Rating Scale in medication (M) and stimulation (S) "on"/"off" states. With DBS at 9 months, the score improved by 86% to 8.5 in M-"on"/S-"on" and 12.5 in M-"off"/S-"on." Studies of the effects of DBS and concomitant medication may be warranted in selected patients treated by DBS for dystonia.
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