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Potentiated antibodies against morphine: effects on biogenic amines and lipid peroxidation in chronically morphinized
A M Titkova1, S M Kharitonova, I R Pan
1Institute of Neurology, Psychiatry, and Narcology, Ukrainian Academy of Medical Sciences, Kharkov.
Bulletin of Experimental Biology and Medicine
|September 2, 2003
Abstract:
The efficiency of potentiated antibodies against morphine was studied on the model of chronic morphine intoxication. Test antibodies stimulated catecholamine metabolism in the hypothalamus (i.e., prevented initiation of catecholamine- and histaminergic peripheral reactions) and normalized lipid peroxidation.