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04:44
Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
Laryngeal involvement in systemic lupus erythematosus.
A D Teitel1, C R MacKenzie, R Stern
1Department of Medicine and Rheumatology, Hospital for Special Surgery, New York, NY 10021.
Seminars in Arthritis and Rheumatism
|December 1, 1992
Summary
Systemic lupus erythematosus (SLE) can affect the larynx, causing symptoms from hoarseness to airway obstruction. Corticosteroids often resolve these laryngeal manifestations in SLE patients.
Area of Science:
- Rheumatology
- Otolaryngology
- Pulmonology
Background:
- Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with diverse clinical manifestations.
- Laryngeal involvement in SLE, though uncommon, can present with a spectrum of pathologies, impacting the upper airway.
Observation:
- This report details four cases of laryngeal involvement in SLE, reviewing 97 patients.
- Observed manifestations included laryngeal edema (28%) and vocal cord paralysis (11%).
- Symptoms like hoarseness, dyspnea, and vocal cord paralysis were common.
Findings:
- The majority of laryngeal SLE symptoms resolved with corticosteroid therapy.
- Less frequent causes included subglottic stenosis, rheumatoid nodules, and necrotizing vasculitis.
- Clinical presentation varied from asymptomatic to life-threatening airway compromise.
Implications:
- Laryngeal involvement in SLE presents a diagnostic and therapeutic challenge due to its variable course and multiple potential causes.
- Early recognition and management are crucial for preventing severe upper airway compromise.
- This highlights the importance of considering laryngeal evaluation in SLE patients with relevant symptoms.
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