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Prognostic factors in renal cell carcinoma
James A Kontak1, Steven C Campbell
1Department of Urology and The Cardinal Bernardin Cancer Center, Loyola University Medical Center, 2160 S. 1st Avenue, Building 54, Room 237, Maywood, IL 60153, USA.
The Urologic Clinics of North America
|September 5, 2003
Summary
Prognostic factors for renal cell carcinoma (RCC) aid patient care and clinical trial stratification. Tumor stage is key, but other factors like grade and size also offer valuable prognostic information for RCC.
Area of Science:
- Oncology
- Urology
Background:
- Established prognostic factors are crucial for renal cell carcinoma (RCC) management.
- These factors aid in patient counseling and stratification for clinical trials.
Purpose of the Study:
- To review the established prognostic factors for renal cell carcinoma (RCC).
- To highlight the utility of these factors in patient management and research.
Main Methods:
- Review of established prognostic factors for renal cell carcinoma (RCC).
- Analysis of clinical signs, symptoms, tumor characteristics, and molecular data.
Main Results:
- Tumor stage is the most significant prognostic factor for RCC.
- Clinical signs, symptoms, tumor grade, size, histologic subtype, DNA content, and nuclear morphometry also provide prognostic value.
- Integration of these factors shows promise for improved patient stratification.
Conclusions:
- Prognostic factors are essential for rational patient stratification and management in RCC.
- Future research will likely incorporate molecular factors for enhanced prognostic accuracy in RCC.