Darier disease: sustained improvement following reduction mammaplasty

Darier disease is an autosomal-dominant inherited genodermatosis. A woman is described who had Darier disease and hereditary spherocytosis whose inframammary Darier disease had dramatic and sustained improvement following reduction mammaplasty. The postoperative resolution of the dermatosis beneath the patient's breasts introduces the possibility that, when appropriately indicated, breast reduction surgery may have a potential role in the management of severe inframammary Darier disease.