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Late-onset diffuse lamellar keratitis.
Rie Amano1, Koji Ohno, Kimiya Shimizu
1Department of Ophthalmology, Kitasato University, Kanagawa, Japan.
Japanese Journal of Ophthalmology
|September 12, 2003
Summary
Diffuse lamellar keratitis (DLK) can manifest late, up to three months after laser in situ keratomileusis (LASIK) surgery. Prompt treatment with topical corticosteroids effectively resolves these late-onset DLK cases.
Area of Science:
- Ophthalmology
- Corneal Surgery
- Inflammatory Eye Conditions
Background:
- Diffuse lamellar keratitis (DLK) presents as infiltrates at the LASIK interface.
- Typically, DLK is culture-negative and non-infectious.
- Most DLK cases appear within two weeks post-LASIK.
Observation:
- Two cases of DLK occurring three months after LASIK were documented.
- Patients presented with delayed-onset DLK symptoms.
Findings:
- Intensive topical corticosteroid treatment was administered.
- Rapid improvement in visual acuity and clinical signs was observed.
- Slit-lamp biomicroscopy confirmed resolution of infiltrates.
Implications:
- DLK can present significantly later than commonly observed.
- Topical corticosteroids are an effective treatment for late-onset DLK.
- This finding expands the known timeline for DLK post-LASIK.