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Updated: Jul 27, 2026

Intracoronary Acetylcholine Provocation Testing for Assessment of Coronary Vasomotor Disorders
Published on: August 18, 2016
Vasospasm-induced heart block
K McCauley1, C Lloyd, H C Herrmann
1University of Pennsylvania School of Nursing, Philadelphia, Pennsylvania, USA.
Insights
Elderly patients with cardiac risk factors experiencing syncope and chest pain may have coronary vasospasm causing conduction deficits. This case highlights the link between coronary artery issues and heart rhythm problems.
Area of Science:
- Cardiology
- Electrophysiology
Background:
- Syncope in elderly patients with carotid disease and cardiac risk factors presents diagnostic challenges.
- Coronary artery disease and conduction abnormalities can coexist.
Observation:
- A case study of an elderly woman with new-onset chest pain and syncope.
- The patient had a history of carotid disease and multiple cardiac risk factors.
Findings:
- Coronary vasospasm was identified as the cause of the syncopal episode.
- Conduction deficits were observed in conjunction with coronary vasospasm.
- A relationship between coronary artery anatomy and conduction abnormalities was discussed.
Implications:
- This case underscores the importance of considering coronary vasospasm in elderly patients with syncope and chest pain.
- Understanding the link between coronary artery defects and conduction abnormalities is crucial for diagnosis and treatment.
- Highlights the need for comprehensive cardiac evaluation in patients with syncope and risk factors.
Abstract:
A syncopal episode in an elderly patient with a history of carotid disease, multiple cardiac risk factors, and new onset chest pain presents diagnostic challenges. This case study describes the experience of a woman with coronary vasospasm accompanied by conduction deficits. The patient's history, diagnostic work-up, and treatment program are presented. The relationship between the coronary artery anatomic defects and the conduction abnormalities are discussed.
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