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Enantioselective chromenone benzoxazole receptor for glutamic acid and its derivatives
José V Hernández1, Ana I Oliva, Luis Simón
1Departamento de Química Orgánica, Plaza de los Caídos 1-5, Universidad de Salamanca, Salamanca, E-37008, Spain. romoran@usal.es
The Journal of Organic Chemistry
|September 13, 2003
Abstract:
Combination of a binaphthyl unit with chromenone benzoxazole fragments provided a chiral receptor that is enantioselective for glutamic acid and its derivatives. The receptor racemic mixture was resolved by TLCs impregnated with (R,R)-thiodilactic acid. High association constants were measured for dansylglutamic acid, using a fluorescent method. This receptor can be used for the resolution of the tosylglutamic acid racemic mixture.