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Updated: Jul 20, 2026

Murine Salivary Functional Assessment via Pilocarpine Stimulation Following Fractionated Radiation
Published on: May 4, 2018
[Age-related changes in the secretory function of the salivary glands]
Abstract:
A total of 326 healthy subjects aged 21 to 80 were examined. Total sialometry without stimulation and that stimulated with supermint chewing gum was carried out. Mixed salivary secretion in health was found to make up approximately 3.4 ml in 10 min. Salivary secretion stimulation with the chewing gum enhanced this secretion 1.5-3 times. Salivary secretion was found to decrease with age. The maximal secretion levels were found in both men and women aged 21 to 30, being higher in men. Normal values of mixed salivary secretion of men and women can be estimated according to the following formulae: for men it is equal to [-0.09(X-25) +5.71] ml, for women to [-0.06(X-25) +4.22] ml, where X is the subject's age in years.
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