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[Primary breast cancer: conservation therapy].

A Kuten1, F Hilu, J Halpern

  • 1Northern Israel Oncology Center, Rambam Medical Center, Haifa.

Harefuah
|April 1, 1992
PubMed
Summary
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This retrospective study of 200 breast cancer patients treated with breast conservation surgery found good cosmetic outcomes and low recurrence rates. Adjuvant therapies and radiotherapy contributed to favorable results in early-stage breast cancer management.

Area of Science:

  • Oncology
  • Surgical Oncology
  • Radiation Oncology

Context:

  • Retrospective analysis of 200 primary breast cancer patients treated between 1981-1988.
  • Focus on breast conservation therapy (BCT) outcomes.
  • Inclusion of diverse pathological and clinical stages.

Purpose:

  • To evaluate the efficacy and outcomes of breast conservation therapy for primary breast cancer.
  • To assess recurrence rates, metastatic spread, and cosmetic results following BCT.
  • To analyze the impact of adjuvant therapies and radiotherapy protocols.

Summary:

  • 58% of patients had Stage I or IIA/IIB disease; 8% had clinical Stages I-II.
  • Surgical margins varied, with 45% having good excision.
  • Adjuvant therapy was administered to 52.5%; radiotherapy included whole breast irradiation with boosts.

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  • Cosmetic results were rated good (96%) or fair (4%) one year post-treatment.
  • Local recurrence occurred in 5.5%, with 2.5% developing lymph node metastases.
  • Distant metastases were observed in 10% of patients.

    • Impact:

    • Demonstrates the long-term viability and positive cosmetic outcomes of breast conservation surgery.
    • Highlights the role of adjuvant therapies and radiotherapy in improving breast cancer management.
    • Provides valuable data for oncologists and surgeons regarding BCT in early-stage breast cancer.