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Cytogenetics of a case of eccrine spiradenoma
T Dijkhuizen1, E van den Berg, P G Nikkels
1Department of Medical Genetics, University of Groningen, The Netherlands.
Human Pathology
|September 1, 1992
Abstract:
A cytogenetic study of an eccrine spiradenoma and two lymph node metastases, with a growth pattern and microscopic appearance typical for benign eccrine spiradenoma, revealed a 46,XY-5,del(16)(q22),+mar(t(?;5)(?::5q13----5qter)) karyotype. The finding of the same abnormal karyotype in the tumor and the metastases suggests a relationship between the chromosomal abnormalities and the clinical malignant behavior of this morphologic benign tumor.