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[Pneumococcal meningitis from 1974 to 1984]
J Vukadinov1, N Madle-Samardzija, M Bogdanović
1Klinika za infektivne i dermatoveneroloske bolesti, Medicinski fakultet, Novi Sad.
Abstract:
We examined a group of 22 patients presented with the acute infective meningeal syndrome. Lumbar punction confirmed diagnosed purulent meningitis--meningoencephalitis, and bacteriologic liquor culture identified Streptococcus pneumoniae as a cause of the disease. Patients were mostly aged over 30. Clinical picture revealed signs of general infection and the meningeal syndrome. The severity of the disease was assessed on the basis of apparent signs of general infection, state of consciousness and endotoxic shock symptoms. Severe consciousness disorders were present in 16 (72.72%) patients. In our patients possible pneumococcus infection foci were: sinusitis, otitis media, pneumonia, mastoiditis and adnexitis. Lethal outcome occurred in 5 (22.72%) patients. In the therapy we used penicillin, chloramphenicol and ampicillin along with corticosteroid administration.
Insights
Streptococcus pneumoniae caused acute meningitis in adults, often leading to severe consciousness disorders and a 22.72% mortality rate despite antibiotic and corticosteroid treatment.
Area of Science:
- Infectious Diseases
- Neurology
- Microbiology
Context:
- Acute infective meningeal syndrome in adults.
- Purulent meningitis and meningoencephalitis diagnosis.
- Focus on Streptococcus pneumoniae etiology.
Purpose:
- To analyze clinical presentation, severity, and outcomes of Streptococcus pneumoniae meningitis.
- To evaluate treatment strategies including antibiotics and corticosteroids.
Summary:
- A study of 22 adult patients with Streptococcus pneumoniae meningitis.
- Clinical signs included general infection and meningeal syndrome; 72.72% had severe consciousness disorders.
- Identified infection foci: sinusitis, otitis media, pneumonia, mastoiditis, adnexitis.
- Mortality rate was 22.72%; treatment involved penicillin, chloramphenicol, ampicillin, and corticosteroids.
Impact:
- Highlights the significant morbidity and mortality associated with pneumococcal meningitis in adults.
- Informs clinical management and emphasizes the need for prompt diagnosis and aggressive therapy.
- Underscores potential infection sources for Streptococcus pneumoniae.