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Nuclear magnetic resonance (NMR) spectroscopy: applications to protein structure and engineering
1School of Biochemistry, University of New South Wales.
Abstract:
High-resolution nuclear magnetic resonance (NMR) spectroscopy has developed into a powerful method for determining the complete three-dimensional structures of proteins in solution. This article reviews current applications of this technique, with particular emphasis on areas of relevance to biotechnology, including protein engineering and protein design.