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Molecular genetics of sex determination in C. elegans
1Department of Biochemistry, College of Agriculture and Life Sciences, University of Wisconsin-Madison 53706, USA.
Trends in Genetics : TIG
|May 1, 1992
Abstract:
Sexual fate in the nematode Caenorhabditis elegans is controlled by a group of genetically well-characterized genes. Several of these sex-determining genes have now been analysed at the molecular level. Transcriptional regulation is likely to control both commitment to a single sexual fate and maintenance of that decision; in addition, intercellular signalling appears to coordinate the sexual fates of cells throughout the animal to adopt a single sexual fate.