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Pharmacokinetics of intragraft iloprost infusion during femoro-crural reconstruction
F C Smith1, M Hildebrand, H R Watson
1Department of Vascular Surgery, Queen Elizabeth Hospital, Birmingham, UK.
Agents and Actions. Supplements
|January 1, 1992
Pharmacokinetics of a single intra-graft infusion of 3000ng iloprost during femoro-crural bypass surgery have been investigated. Plasma iloprost concentrations, biphasic half-lives, and total drug clearances were found to occur within ranges demonstrated for IV infusion dose regimens.
Pharmacokinetics of a single intra-graft infusion of 3000ng iloprost during femoro-crural bypass surgery have been investigated. Plasma iloprost concentrations, biphasic half-lives, and total drug clearances were found to occur within ranges demonstrated for IV infusion dose regimens.