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Partial laryngectomy in transglottic carcinoma.

A Prlić1, Z Krajina

  • 1Department of Otorhinolaryngology, General Hospital, Osijek, Croatia.

Acta Medica Croatica : Casopis Hravatske Akademije Medicinskih Znanosti
|January 1, 1992
PubMed
Summary

Partial laryngectomy for transglottic carcinoma showed significantly better survival and lower metastasis rates compared to total laryngectomy. This suggests less radical surgery may be a viable option for select patients.

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Area of Science:

  • Otolaryngology
  • Oncology
  • Surgical Oncology

Background:

  • Transglottic carcinoma presents a significant challenge in head and neck oncology.
  • Treatment decisions for transglottic carcinoma involve balancing oncologic control with laryngeal function preservation.

Purpose of the Study:

  • To compare the outcomes of total laryngectomy versus partial laryngectomy in patients with transglottic carcinoma.
  • To evaluate survival rates and the incidence of neck metastases for each surgical approach.

Main Methods:

  • Retrospective analysis of 119 transglottic carcinoma cases treated between 1973 and 1982.
  • Group 1: 20 patients underwent total laryngectomy.
  • Group 2: 99 patients underwent partial laryngectomy (vertical and combined), with reconstruction using sternohyoid fascia and selective cartilage resection.

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Main Results:

  • Total laryngectomy group: 5-year survival rate of 50% (10/20), with 30% (6/20) experiencing neck metastases.
  • Partial laryngectomy group: 5-year survival rate of 70% (70/99), with 19% (19/99) experiencing neck metastases.
  • Partial laryngectomy involved reconstruction and, when indicated, partial cricoid and total arytenoid resection.

Conclusions:

  • Partial laryngectomy demonstrates superior survival rates and a reduced incidence of neck metastases compared to total laryngectomy for transglottic carcinoma.
  • These findings support the consideration of partial laryngectomy as a potentially more effective treatment strategy for select patients with transglottic carcinoma.