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A histologic study of nonmorphogenetic forms of hereditary hearing impairment
R J Smith1, K P Steel, C Barkway
1Department of Otolaryngology-Head and Neck Surgery, University of Iowa, Iowa City 52242.
Archives of Otolaryngology--Head & Neck Surgery
|October 1, 1992
Abstract:
It appears that many forms of syndromic and nonsyndromic hereditary hearing impairment are secondary to either neuroepithelial or cochleosaccular dysfunction. Making this distinction can be difficult in human temporal bone specimens; however, this added knowledge may ultimately provide prognostic and therapeutic information in hearing habilitation. Fundamental studies using animal models of different types of hereditary deafness may also prove useful in this respect.