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Published on: June 23, 2020
Osteomyelitis and intervertebral discitis caused by Pseudomonas pickettii
1Department of Internal Medicine, University of Michigan School Medicine, Ann Arbor 48109-0680.
Abstract:
Pseudomonas pickettii, a nonfermenting, gram-negative rod, is rarely pathogenic. Previous reports of infection with P. pickettii have largely involved direct contamination of supplies presumed to be sterile. We describe a case of vertebral osteomyelitis and intervertebral discitis caused by P. pickettii in a debilitated patient. The aggressive nature of this infection demonstrates that P. pickettii may be a more invasive organism than previously noted, particularly in hosts with weakened immunity secondary to underlying disease.
Insights
Pseudomonas pickettii, a rare pathogen, caused severe vertebral osteomyelitis and discitis in an immunocompromised patient. This case highlights its potential for invasive infection beyond mere contamination events.
Area of Science:
- Medical Microbiology
- Infectious Diseases
- Clinical Case Study
Background:
- Pseudomonas pickettii is a Gram-negative bacterium typically associated with rare, non-invasive infections.
- Previous P. pickettii infections were often linked to contaminated medical supplies.
- The pathogenicity of P. pickettii in invasive disease remains under-recognized.
Observation:
- A case of vertebral osteomyelitis and intervertebral discitis is presented.
- The infection was caused by the bacterium Pseudomonas pickettii.
- The affected patient was debilitated with weakened immunity due to underlying disease.
Findings:
- Pseudomonas pickettii demonstrated an aggressive infection pattern.
- The bacterium caused severe bone and disc infection in the spine.
- This indicates P. pickettii can be a significant invasive pathogen.
Implications:
- The findings suggest P. pickettii may be more invasive than previously understood.
- Immunocompromised individuals are at higher risk for severe P. pickettii infections.
- Clinical awareness of P. pickettii's invasive potential is crucial for timely diagnosis and treatment.
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