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T Cells Capture Bacteria by Transinfection from Dendritic Cells
Published on: January 13, 2016
Activation of T cells in vivo using anti-CD3 and staphylococcal enterotoxins
J A Bluestone1, D S Bruce, K A Newell
1Ben May Institute, University of Chicago, IL 60637.
One of the major problems in clinical immunity is that neoplastic and virally infected cells are insufficiently immunogenic to trigger an immune response. During the past several years, our laboratory has explored the use of T-cell-specific reagents including monoclonal antibodies (MAbs) and staphylococcal enterotoxins to amplify immune responses. This report summarizes our efforts to augment immunity with these agents.
One of the major problems in clinical immunity is that neoplastic and virally infected cells are insufficiently immunogenic to trigger an immune response. During the past several years, our laboratory has explored the use of T-cell-specific reagents including monoclonal antibodies (MAbs) and staphylococcal enterotoxins to amplify immune responses. This report summarizes our efforts to augment immunity with these agents.
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