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[Severe exacerbation of chronic hepatitis B following interferon therapy]
T Laskus1, M Radkowski, J Cianciara
1Zakładu Immunopatologii Instytutu Chorób Zakaźnych i Pasozytniczych Ak. Med., Warszawie.
Abstract:
A patient with chronic active hepatitis B was treated with interferon alpha. Inhibition of HBV replication was associated with severe exacerbation of hepatitis. Treatment of chronic hepatitis B with interferon may lead to transient decompensation of liver function, especially in patients with high activity of morphological changes.