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Intrastromal photorefractive keratectomy with a new optically coupled laser probe
J Taboada1, R H Poirier, R W Yee
1Laser Research and Development Program, Ltd, San Antonio, TX 78229.
Refractive & Corneal Surgery
|September 1, 1992
Summary
Intrastromal keratectomy uses laser pulses to create vacuoles in the cornea, altering its shape. This novel procedure offers a new method for achieving corneal refractive power.
Area of Science:
- Ophthalmology
- Biomedical Engineering
- Laser Surgery
Background:
- Intrastromal keratectomy is an emerging technique for modifying corneal curvature.
- It involves creating vacuolated regions within the corneal stroma.
Purpose of the Study:
- To investigate the efficacy of intrastromal keratectomy for refractive correction.
- To evaluate the tissue effects and refractive outcomes of this procedure.
Main Methods:
- Utilized diffraction-limited 1064-nanometer Nd:YAG laser pulses delivered via a novel probe.
- Applied the laser to eye-bank, rabbit, and primate corneas, inducing plasma points without shockwaves.
- Assessed refractive changes using slit-lamp microscopy, keratoscopy, and electron microscopy.
Main Results:
- Observed immediate refractive effects comparable to refractive keratotomy.
- Created localized intrastromal vacuoles (approx. 100 microns diameter) with high precision (20-micron variability).
- Vacuoles resolved within 24-48 hours, with minimal (<0.5 micron) transition zones.
Conclusions:
- Intrastromal keratectomy is a viable method for achieving corneal refractive power.
- The procedure demonstrates precise tissue modification and temporary refractive alteration.
