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AToxMss--from a space proven payload to a validated testsystem in ecotoxicology
K Slenzka1, M Duenne, B Jastorff
1OHB-System AG, Dept. Life Science, Bremen, Germany. slenzka@ohb-system.de
Summary
The Closed Equilibrated Biological Aquatic System (C.E.B.A.S.-Minimodule) is a space-qualified aquatic microcosm. An improved version, the Closed Biological Research Unit (C.B.R.U.), is being developed for ecotoxicology research.
Area of Science:
- Ecotoxicology
- Aquatic Systems Biology
- Space Biology
Background:
- The C.E.B.A.S.-Minimodule is a space-qualified aquatic microcosm (8.6 L) capable of supporting multiple aquatic species.
- Its characteristics include a closed system, high standardization, and the potential for long-term (over 4 weeks) studies involving organisms from different trophic levels.
- These features make it suitable for ecotoxicological research.
Purpose of the Study:
- To develop an improved aquatic microcosm, the Closed Biological Research Unit (C.B.R.U.), for scientific and commercial ecotoxicology.
- To advance Aquatic EcoToxicology in a Multispecies System (AToxMss) through a collaborative R&D project.
- To establish a standardized and reliable platform for assessing the impact of chemicals on aquatic ecosystems.
Main Methods:
- Development of the C.B.R.U. module based on the C.E.B.A.S.-Minimodule.
- Parameter determination for indicating chemical impact on biological systems.
- Selection of appropriate test substances and manufacturing of functional modules.
- System calibration using well-known toxic substances and chemicals in upcoming test runs.
Main Results:
- Three functional C.E.B.A.S.-Minimodule units have been manufactured and verified for ecotoxicological research.
- Project phases including parameter determination and test substance selection are completed.
- The project is progressing towards system calibration with toxic substances.
Conclusions:
- The C.B.R.U. represents a significant advancement in aquatic microcosm technology for ecotoxicology.
- The AToxMss project is successfully developing a robust platform for multispecies aquatic ecotoxicology.
- Upcoming calibration runs will validate the C.B.R.U.'s efficacy in assessing chemical impacts.