Related Experiment Videos
Single dose povidone-iodine on thyroid functions and urinary iodine excretion
Deniz Yilmaz1, H Tahsin Teziç, Pelin Zorlu
1Dr. Sami Ulus Children's Hospital, Ankara, Turkey. dayilmaz2002@yahoo.com
Indian Journal of Pediatrics
|September 27, 2003
Summary
Single-dose povidone-iodine skin disinfection did not alter thyroid function in newborns. While urinary iodine levels increased in preterm and full-term infants, no significant thyroid disorders were observed.
Area of Science:
- Neonatal medicine
- Endocrinology
- Pediatric surgery
Background:
- Povidone-iodine is a common antiseptic used in neonatal care.
- Concerns exist regarding potential effects of iodine exposure on the developing thyroid in neonates.
Purpose of the Study:
- To evaluate the impact of a single povidone-iodine dose on thyroid function and iodine excretion in newborns.
- To assess the risk of thyroid dysfunction following antiseptic use in neonates.
Main Methods:
- Serum thyrotropin and thyroxine levels were measured in preterm, full-term newborns, and infants.
- Urinary iodine excretion was assessed post-application of povidone-iodine.
- Thyroid function was monitored after single-dose skin disinfection.
Main Results:
- No statistically significant changes in serum thyrotropin or thyroxine levels were observed across all infant groups (p>0.05).
- A significant elevation in urinary iodine excretion was noted in both preterm and full-term newborn groups (p<0.05).
Conclusions:
- Single-dose povidone-iodine application for skin disinfection poses no significant risk of thyroid disorders in newborns.
- Transient increases in urinary iodine do not correlate with adverse thyroid function changes in the neonatal population.