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Updated: Aug 15, 2026

Rapid In Vivo Assessment of Adjuvant's Cytotoxic T Lymphocytes Generation Capabilities for Vaccine Development
Published on: June 19, 2018
[The difficulty of obtaining immunologic responses in mucosae. Use of coadjuvants]
1Laboratorio de Inmunología, División de Posgrádo, Escuela de Medicina Ignacio Chávez, Universidad Michoacana San Nicolás de Hidalgo, Morelia, Michoacán, México. arorozco@hotmail.com
Abstract:
The search of immunogenicity represents a real problem to be solved with the new techniques to vaccines design. Despite of numerous initiatives to increase the immune response at mucosal sites, there are few substances available to exert an adequate immunogenicity in mucosal compartments. On this hand the research on mucosal adjuvants has arise interest. Mechanism of both: immunogenicity and adjuvanticity, were reviewed putting emphasis mainly in two mucosal adjuvants, cholera toxin and the protoxin Cry1Ac from Bacillus thuringiensis.
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