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Optical coherence tomographic findings in acute exudative polymorphous vitelliform maculopathy.
Vanessa Cruz-Villegas1, Natalia Villate, Robert W Knighton
1Department of Ophthalmology, University of Miami, School of Medicine, Bascom Palmer Eye Institute, Miami, Florida 33136, USA.
American Journal of Ophthalmology
|October 1, 2003
Summary
This study describes two cases of acute exudative polymorphous vitelliform maculopathy, a condition causing transient, multifocal vitelliform lesions. Optical coherence tomography showed characteristic subretinal deposits, aiding diagnosis.
Area of Science:
- Ophthalmology
- Retinal Diseases
- Medical Imaging
Background:
- Acute exudative polymorphous vitelliform maculopathy (AEPVM) is a rare condition.
- Understanding its clinical presentation and imaging features is crucial for accurate diagnosis.
Observation:
- Two cases of AEPVM presented with sudden blurred vision and bilateral, symmetric vitelliform lesions.
- Fluorescein angiography showed faint early hyperfluorescence in perimacular lesions.
- Optical coherence tomography (OCT) revealed anterior photoreceptor displacement by subretinal deposits.
Findings:
- OCT demonstrated a characteristic hypereflective subretinal layer and an underlying hyporeflective space.
- No subretinal fluid was observed, differentiating it from other macular diseases.
- Electrooculogram (EOG) results were abnormal, but lesions resolved within 4-8 months.
Implications:
- Transient multifocal vitelliform lesions are indicative of AEPVM.
- OCT findings are similar to adult-onset foveomacular vitelliform dystrophy, aiding differential diagnosis.
- Early diagnosis and monitoring of AEPVM can guide patient management.