Related Experiment Video
Updated: Aug 11, 2026

11:34
Breathing-controlled Electrical Stimulation (BreEStim) for Management of Neuropathic Pain and Spasticity
Published on: January 10, 2013
Functional electrical stimulation (FES) for spinal cord injury
1Department of Neurosurgery, Fujita Health University, Toyoake, Aichi, Japan. neuron@fujita-hu.ac.jp
Acta Neurochirurgica. Supplement
|October 2, 2003
Summary
Phrenic nerve stimulation with a breathing pacemaker restored respiratory motion in a patient with spinal cord injury. This device offers improved mobility and quality of life compared to mechanical ventilators.
Area of Science:
- Neurology
- Respiratory Medicine
- Biomedical Engineering
Background:
- Upper cervical spinal cord injury can lead to severe respiratory disturbances.
- Mechanical ventilators are a common but often restrictive treatment option.
Observation:
- A breathing pacemaker system was implemented to restore respiratory motion via phrenic nerve stimulation.
- The system successfully restored respiratory function in a patient with respiratory disturbance.
Findings:
- Breathing pacemakers offer a more physiological approach to respiratory support compared to mechanical ventilation.
- The system significantly enhanced patient mobility and quality of life (QOL).
- Despite high initial costs, long-term cost-effectiveness is probable with extended daily use.
Implications:
- Increased adoption of breathing pacemakers in Japan is recommended for spinal cord injury patients.
- Addressing economic and logistical support is crucial for wider implementation.
- Phrenic nerve stimulation presents a promising alternative for managing respiratory insufficiency.

