[Pangenome]

Area of Science:

• Genomics
• Evolutionary Biology
• Bioinformatics

Context:

• Understanding the interconnectedness of genetic information across diverse organisms is crucial.
• Existing frameworks do not fully capture the totality of genetic material, including viral and microbial genomes.
• The dynamic nature of genetic exchange necessitates a new conceptual model.

Purpose:

• To formulate a novel conception of general interaction between the genetic information of different organisms.
• To introduce and define the concept of 'Pangenom' as the total sum of genes from living organisms and viruses.
• To explore the structural features and regulatory processes governing Pangenom's stability and variability.

Summary:

• The Pangenom concept encompasses the complete set of genes from all living organisms and viruses, highlighting their interactions.
• Analysis of Pangenom structure reveals key processes that control its conservation and evolutionary changes.
• This framework facilitates a unified view of genetic information flow and evolution across the biosphere.

Impact:

• Enables improved prognosis of epidemic situations, including the emergence of novel pathogens.
• Facilitates the development of advanced diagnostic and prophylactic methods for oncological diseases.
• Provides a basis for evaluating the potential consequences of molecular genetics and gene engineering interventions.