Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Limb body wall complex.

Sanjeev Managoli1, Pushpa Chaturvedi, Krishna Y Vilhekar

  • 1Departments of Pediatrics and Pathology, Mahatma Gandhi Institute of Medical Sciences, Sevagram, Wardha, Maharashtra-442 102, India. drsanjeevsm@yahoo.com

Indian Pediatrics
|October 8, 2003
PubMed
Summary

This case report details a rare Limb Body Wall Complex in a stillborn neonate. The complex involved abdominal defects, spinal issues, limb abnormalities, and unusual organ associations.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Concurrent acute disseminated encephalomyelitis and Guillain-Barré syndrome in a child.

Journal of pediatric neurosciences·2015
Same author

A case report of ectopia cordis and omphalocele.

Indian journal of human genetics·2014
Same author

Congenital malformations at birth in Central India: A rural medical college hospital based data.

Indian journal of human genetics·2011
Same author

Distribution of blood pressure in school going children in rural area of Wardha district, Maharashatra, India.

Annals of pediatric cardiology·2010
Same author

Yale Observation Scale for prediction of bacteremia in febrile children.

Indian journal of pediatrics·2009
Same author

Antenatal detection of renal malformations.

Indian pediatrics·2009

Area of Science:

  • Medical Genetics
  • Developmental Biology
  • Neonatology

Background:

  • Limb Body Wall Complex (LBWC) is a severe congenital disorder.
  • It is characterized by defects in the abdominal wall, limbs, and spine.
  • LBWC has a high mortality rate, often resulting in stillbirth or neonatal death.

Observation:

  • A preterm, low birth weight, stillborn neonate presented with LBWC.
  • The neonate exhibited an abdominal wall defect with organ evisceration into an amnio-peritoneal sac, a short body stalk, spinal torsion with scoliosis, and limb defects.
  • Unusual findings included an absent thymus, kidney interstitial calcification, and a maternal history of oral contraceptive use during early pregnancy.

Findings:

  • The case illustrates the diverse and severe phenotypic manifestations of Limb Body Wall Complex.
  • The presence of absent thymus and kidney calcification suggests potential broader systemic involvement or specific etiological factors.
  • The association with maternal oral contraceptive exposure warrants further investigation into potential teratogenic links.

Implications:

  • This case contributes to the understanding of the spectrum of Limb Body Wall Complex.
  • It underscores the importance of detailed examination in neonates with complex congenital anomalies.
  • Further research is needed to elucidate the etiology and pathogenesis of LBWC, particularly concerning unusual associated findings and potential environmental influences.

Related Experiment Videos