Implantable drug-releasing biodegradable microspheres for local treatment of brain glioma
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1Department of Neurosurgery, Universitaire d'Angers, Angers Cedex, France. phmenei@chu-angers.fr
Acta Neurochirurgica. Supplement
|October 9, 2003
Abstract:
Our group have developed a new method of drug delivery into the brain using implantable biodegradable microspheres. In this mini-review, we describe the development, preclinical studies and clinical trials involving 5-fluorouracil-releasing microspheres for interstitial radiosensitization of malignant glioma. Future developments concerning these microspheres for treatment of brain tumors are presented.
