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Related Experiment Videos

Symptom control.

Victor T Chang1, Jane Ingham

  • 1UMDNJ/New Jersey Medical School, VA New Jersey Health Care System, 385 Tremont Avenue, East Orange, NJ 07018, USA. victor.chang@med.va.gov

Cancer Investigation
|October 10, 2003
PubMed
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This review covers advances in symptom assessment and control for cancer patients, focusing on therapy-related and disease-related symptoms to improve patient care and clinical trial outcomes.

Area of Science:

  • Oncology
  • Palliative Care
  • Clinical Research

Background:

  • Symptom control is a critical aspect of patient care, necessitating standardized assessment and definitions of improvement.
  • Understanding symptom control is vital for interpreting clinical trial data and guiding patient management.

Purpose of the Study:

  • To review advances in symptom assessment and control strategies in oncology.
  • To explore the role of symptom control as an endpoint in clinical trials.
  • To survey therapy-related and disease-related symptoms and their management.

Main Methods:

  • Literature review of advances in symptom assessment and definitions of improvement.
  • Survey of symptom control in two categories: therapy-related symptoms (chemotherapy, radiation, hormonal therapy, surgery) and disease-related symptoms (palliative oncologic approaches).

Related Experiment Videos

  • Examination of symptom control as a clinical trial endpoint.

    • Main Results:

    • Chemotherapy-related symptoms include mucositis, emesis, and fatigue; hormonal therapy-related symptoms include hot flashes; radiation-related symptoms include dermatitis, xerostomia, and mucositis.
    • Palliative oncologic approaches address disease-related symptoms such as cancer pain and lack of appetite.
    • Findings are presented in both clinical and research contexts.

    Conclusions:

    • Symptom control is a key goal in patient care, requiring robust assessment and clear definitions of improvement.
    • Further research is needed in specific areas of symptom management.
    • This review provides guidance for interpreting symptom control studies in clinical and research settings.