Related Experiment Video
Updated: Jun 21, 2026

Detection of Architectural Distortion in Prior Mammograms via Analysis of Oriented Patterns
Published on: August 30, 2013
False-positive result and reattendance in the Ontario Breast Screening Program
A M Chiarelli1, V Moravan, E Halapy
1Cancer Care Ontario, Department of Public Health Sciences, University of Toronto, Canada. anna_chiarelli@cancercare.on.ca
Objective:
To determine the association between initial screen result and returning for a second screen in an organised breast screening programme for women with a biennial screening recommendation.
Setting:
Women who attended the Ontario Breast Screening Program (OBSP).
Methods:
A retrospective cohort study was conducted of 140723 Ontario women aged 50 years and older who had an initial screen at the OBSP between 1 July 1990 and 31 December 1995 and were followed until 30 June 1998. Rescreening rates at 36 months and risk ratio estimates were calculated using survival methods. Age of women, year of screen, region (within Ontario) and initial screen result were compared. For initial screen results, returning for a second screen was examined by integration of screening centre with an assessment programme and by modality of referral.
Results:
Women with a false-positive result were less likely to return for a second screen as were women aged 70 and older and those living in regions of Ontario with fewer OBSP screening centres. However, there were minimal differences in reattendance behaviour by initial screen result for women screened at the OBSP centre with an assessment programme.
Conclusions:
Integration of breast screening and assessment services improved reattendance of women with false-positive screen results within an organised screening programme.
Related Concept Videos
Confirmation Biases
mTOR Signaling and Cancer Progression
The mTOR pathway or the...
Cancer Prevention
Some...
Cancer-Critical Genes II: Tumor Suppressor Genes
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...
The Retinoblastoma Gene
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
Sensitivity, Specificity, and Predicted Value
Sensitivity is the...

