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[Uterine fibroids embolization: results about 454 cases].
J-H Ravina1, A Aymard, N Ciraru-Vigneron
1Cabinet médical, 81, rue d'Amsterdam, 75008 Paris, France. jh.ravina@wanadoo.fr
Gynecologie, Obstetrique & Fertilite
|October 18, 2003
Summary
Uterine artery embolization (UAE) effectively manages symptomatic uterine fibroids, offering a less invasive alternative to surgery. This treatment significantly reduces fibroid size and alleviates symptoms in most patients.
Area of Science:
- Interventional Radiology
- Gynecology
- Vascular Surgery
Background:
- Uterine leiomyomas (fibroids) are common benign tumors causing significant symptoms.
- Symptomatic leiomyomas can lead to menorrhagia and bulk-related issues, impacting quality of life.
- Traditional management often involves surgical interventions with associated risks.
Purpose of the Study:
- To evaluate the efficacy of uterine artery embolization (UAE) as a primary treatment for symptomatic leiomyomas.
- To assess symptom control and reduction in uterine and leiomyoma volume post-UAE.
- To determine the safety and complication profile of UAE in this patient cohort.
Main Methods:
- UAE was performed on 454 patients with symptomatic leiomyomas.
- Effectiveness was measured by clinical and imaging assessments at 3, 6, and 9 months.
- Key outcome measures included symptom resolution and volumetric changes of the uterus and fibroids.
Main Results:
- A low failure rate of 9.6% was observed in 433 evaluated patients.
- Symptom relief was achieved in 391 patients (89.8%) by 6 months post-procedure.
- Significant average reduction in dominant fibroid volume was noted: 55% at 6 months and 70% at 1 year.
- Pregnancy occurred in 27 women (30 pregnancies) with rare severe complications.
Conclusions:
- UAE is an effective primary treatment for symptomatic uterine leiomyomas.
- It presents a safe and minimally invasive alternative to hysterectomy or myomectomy.
- The technique shows promising potential for conservative management of fibroids.