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[Peritoneal tuberculosis simulating advanced ovarian carcinoma: a case report].
S Lantheaume1, S Soler, B Issartel
1Service de gynécologie-obstétrique, CHT Magenta, 7, avenue Paul-Doumer, BP J5, 98800 Nouméa, Nouvelle-Calédonie. steph.lanth@wanadoo.fr
Gynecologie, Obstetrique & Fertilite
|October 18, 2003
Summary
Disseminated peritoneal tuberculosis can mimic ovarian cancer, presenting a diagnostic challenge. Early diagnosis and treatment are crucial for managing this re-emerging disease.
Area of Science:
- Infectious Diseases
- Oncology
- Gastroenterology
Background:
- Disseminated peritoneal tuberculosis (DPTB) is a rare form of tuberculosis, comprising 1-3% of all TB cases.
- DPTB often presents with non-specific symptoms and imaging findings, making diagnosis difficult.
- There is a notable increase in tuberculosis cases in Western countries.
Observation:
- A 43-year-old woman presented with symptoms suggestive of advanced ovarian cancer, including a suspected latero-uterine mass and elevated serum CA 125 levels.
- Initial diagnostic interpretations based on pleural and peritoneal fluid analysis were misleading.
- Laparotomy with biopsy was essential for accurate diagnosis of disseminated peritoneal tuberculosis.
Findings:
- The patient's symptoms, imaging, and elevated CA 125 levels mimicked disseminated ovarian carcinoma.
- Histopathological examination via biopsy confirmed disseminated peritoneal tuberculosis.
- Multidrug anti-tuberculosis therapy led to symptom resolution and normalization of CA 125 levels after 3 months.
Implications:
- Disseminated peritoneal tuberculosis poses a significant diagnostic challenge, often mistaken for malignancy.
- Increased incidence of tuberculosis necessitates heightened clinical suspicion for DPTB, especially in endemic regions or among returning travelers.
- Accurate and timely diagnosis is critical for effective management and improved patient outcomes.