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Updated: Aug 19, 2026

Minimally Invasive Establishment of Murine Orthotopic Bladder Xenografts
Published on: February 11, 2014
[Minimally-invasive therapy of urinary stones]
1Urologische Klinik, Universitätsklinikum Mannheim. thomas.knoll@uro.ma.uni-heidelberg.de
Abstract:
Open surgery was the standard therapy for urinary calculi up to about 30 years ago. This changed upon introduction of extracorporeal shockwave lithotripsy (ESWL) in 1980, a procedure that is now the primary therapy for 70 % of the patients in western countries. Simultaneously, endourological procedures like ureterorenoscopy (URS) and percutaneous nephrolithotripsy (PCNL) have been improved, and now, modern small diameter and highly efficient instruments offer an ideal alternative to shockwave lithotripsy. Today, minimally-invasive stone treatment has replaced open stone surgery almost completely. This article introduces ESWL, URS and PCNL and discusses indications, outcomes and limitations.
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