Three-dimensional CT angiography in the evaluation of cerebral arteries in acute hemorrhage
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Updated: Aug 30, 2026

A Volumetric Method for Quantification of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage
Published on: July 28, 2018
K V Rajagopal1, B N Lakhkar, D K Acharya
1Department of Radio Diagnosis & Imaging, Kasturba Medical College, Manipal 576-119, Karnataka, India.
Insights
Three-dimensional CT angiography (3D CTA) effectively detects cerebral aneurysms with high sensitivity and specificity. This non-invasive imaging technique aids in identifying aneurysm origin and neck, proving valuable for diagnosis.
Area of Science:
- Neuroradiology
- Medical Imaging
Background:
- Cerebral aneurysms pose a significant risk for subarachnoid hemorrhage.
- Accurate detection and characterization are crucial for effective treatment planning.
Purpose of the Study:
- To evaluate the diagnostic value of non-invasive three-dimensional CT angiography (3D CTA) for detecting cerebral aneurysms.
Main Methods:
- Helical CT acquisition with non-ionic contrast in 50 patients.
- Maximum Intensity Projection (MIP) reconstruction for 3D CTA.
- Comparison with digital subtraction angiography (DSA) in 14 patients.
Main Results:
- 3D CTA detected 38 out of 39 aneurysms (97.4% detection rate).
- High specificity (100%) and sensitivity (97.2%) for aneurysm detection.
- Accurate visualization of aneurysm origin and neck in most cases (97%).
Conclusions:
- 3D CTA is a simple, quick, and non-invasive method for cerebral aneurysm detection.
- It can replace DSA in many cases, particularly for aneurysms in the circle of Willis.
- Provides clear depiction of aneurysm relation to bony landmarks.
Objective:
We conducted this study to demonstrate the value of non-invasive three-dimensional CT angiography (3D CTA) in the detection of a cerebral aneurysm.
Material And Methods:
A helical CT acquisition was obtained using non-ionic contrast media in 50 patients with 1 mm per second table speed, 1 mm collimation, and pitch 1:1. Axial source images were transferred into a workstation console (Advantage windows GE) and CTA was obtained using MIP (Maximum Intensity Projection) reconstruction. Fourteen patients underwent conventional digital subtraction angiography (DSA) after 3D CTA prior to surgery.
Results:
A total of 39 aneurysms were detected in 50 patients. All patients with an aneurysm were operated and the presence of aneurysms was confirmed. 3D CTA detected 38 of these 39 aneurysms. In 37 aneurysms, the origin of the aneurysm and aneurysm neck was adequately visualized. 3D CTA was found to be 100% specific and 97.2% sensitive in picking up cerebral aneurysms. 3D CTA was 97% specific in demonstrating the exact origin and showing the neck of the aneurysm.
Conclusions:
CT angiography is a simple, quick, and non-invasive technique and can replace DSA in most patients with acute subarachnoid hemorrhage aneurysm for the detection and characterization of aneurysms of the circle of Willis. The relation of the aneurysm with bony landmarks was clearly depicted.
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