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Preliminary clinical study on perforating prosthokeratoplasty
Jian Chen1, Jintang Xu, S A Yakimenko
1Department of Ophthalmology, First Affiliated Hospital of Jinan University, Guangzhou 510630, China.
Yan Ke Xue Bao = Eye Science
|October 25, 2003
Summary
Prosthokeratoplasty significantly improved vision in most patients with leucoma who had failed or were unsuitable for traditional keratoplasty. This procedure offers a viable option for restoring sight in challenging cases.
Area of Science:
- Ophthalmology
- Regenerative Medicine
Background:
- Leucoma, or corneal opacity, significantly impairs vision.
- Patients with severe leucoma often have limited treatment options, especially if previous keratoplasty has failed or is not feasible.
Purpose of the Study:
- To evaluate the efficacy of prosthokeratoplasty using the Yakimenko Style keratoprosthesis.
- To assess visual outcomes in patients with leucoma unsuitable for or who failed conventional keratoplasty.
Main Methods:
- The study involved five patients with leucoma resulting from chemical burns or blast injuries.
- Yakimenko Style keratoprosthesis implantation was performed.
- Preoperative visual acuity ranged from light perception to finger counting at 20 cm.
Main Results:
- Four out of five patients experienced significant visual improvement following prosthokeratoplasty.
- Postoperative visual acuity ranged from 0.09 to 0.8.
- One patient showed no change in visual acuity during the follow-up period of 9 months to 3 years.
Conclusions:
- Prosthokeratoplasty is a highly effective treatment for visual rehabilitation in patients with leucoma.
- It serves as a primary option for individuals with leucoma who are not candidates for or have not benefited from penetrating keratoplasty.