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Updated: Aug 30, 2026

Identifying Bone Marrow Microenvironmental Populations in Myelodysplastic Syndrome and Acute Myeloid Leukemia
Published on: November 10, 2023
[Hematologic tumors]
1Nagoya Kyoritu Hospital, 1-172 Hokke, Nakagawa-ku, Nagoya 454-0933, Japan.
Abstract:
Development of cytarabine and daunorubicin has made a cure for acute myeloid leukemia (AML) possible. Current first line chemotherapy is a combination of idarubicin plus cytarabine. Acute promyelocytic leukemia has the highest cure rate among AML due to the introduction of ATRA. Current first line chemotherapy for advanced Hodgkin's lymphoma is ABVD, based upon results of a prospective randomized study comparing MOPP, ABVD and MOPP/ABVD. CHOP has been frequently selected as first line chemotherapy for advanced non-Hodgkin's lymphoma, based upon results obtained in a phase III study that compared CHOP versus second and third generation combinations.
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