Related Experiment Video
Updated: Aug 30, 2026
07:05
Mouse Model of Alloimmune-induced Vascular Rejection and Transplant Arteriosclerosis
Published on: May 17, 2015
Angiographic regression of cardiac allograft vasculopathy after introducing sirolimus immunosuppression
Peter N Ruygrok1, Bruce Webber, Stephen Faddy
1Cardiology Department, Green Lane Hospital, Auckland, New Zealand. pruygrok@adhb.govt.nz
Abstract:
We describe a 33-year-old heart transplant recipient who experienced several episodes of early Grade IIIA rejection and aggressive allograft vasculopathy, seen with serial coronary angiography. Two years after transplantation, we added sirolimus therapy to the patient's immunosuppressive regimen, and a further coronary angiogram 1 year later showed regression of the graft vasculopathy.
