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Distributed three-dimensional fiber Bragg grating refractometer for biochemical sensing.

S Keren1, M Horowitz

  • 1Department of Electrical Engineering, Technion--Israel Institute of Technology, Haifa 32000, Israel.

Optics Letters
|November 1, 2003
PubMed
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We developed a 3-D distributed refractometer using fiber Bragg gratings and spectral interferometry. This sensor enables rapid, localized refractive index measurements for applications like glucose monitoring and evaporation studies.

Area of Science:

  • Optics and Photonics
  • Sensor Technology
  • Biomedical Sensing

Background:

  • Refractive index sensing is crucial for various applications, including chemical analysis and biomedical diagnostics.
  • Existing methods often require large sample volumes or mechanical scanning, limiting their applicability.
  • Distributed sensing offers the potential for spatially resolved measurements within a small volume.

Purpose of the Study:

  • To demonstrate a novel three-dimensional (3-D) distributed refractometer for measuring refractive index in small volumes.
  • To develop a sensor capable of rapid, non-scanning measurements.
  • To showcase the sensor's utility in simultaneous multi-droplet analysis and dynamic process monitoring.

Main Methods:

  • Utilized an evanescent-wave fiber Bragg grating (FBG) as the sensing element.

Related Experiment Videos

  • Employed low-coherence spectral interferometry for interrogating the FBG.
  • Implemented a system for 3-D distributed refractive index measurements without mechanical scanning.

    • Main Results:

    • Successfully demonstrated a 3-D distributed refractometer with high spatial resolution.
    • Achieved simultaneous measurement of glucose concentration in multiple droplets along a single sensor.
    • Monitored the time-dependent evaporation process of a water droplet with high temporal resolution.

    Conclusions:

    • The developed sensor provides a powerful new tool for 3-D distributed refractive index measurements in small volumes.
    • This technique enables novel sensor designs for simultaneous, localized measurements.
    • Potential applications include advanced diagnostics, process monitoring, and microfluidic analysis.